Assistant Professor, Infectious Diseases and Microbiology
Department of Infectious Diseases and Microbiology
2136 Parran Hall; 130 DeSoto Street
Pittsburgh, PA 15261
University of Pittsburgh
Hepatotropic infections and associated diseases including chronic viral hepatitis, chronic liver fluke infections, and co-morbidities (i.e., HIV, fatty liver disease) are major contributors to global morbidity and mortality. Furthermore, disadvantaged and minority populations are disproportionally affected by liver disease in the United States. My research focuses on leveraging regenerative medicine technologies in developing humanized mouse models with autologous human immune and hepatobiliary systems for studying liver infections, immune response, liver disease and co-morbidities including HIV co-infection and fatty liver disease. Additionally, my research program seeks to elucidate the role of innate immune cells, specifically monocytes/macrophages in hepatotropic pathogens (HBV,HCV, liver fluke)-induced immune dysregulation and liver pathogenesis, and the mechaniss of co-morbidities (HIV, fatty liver disease).